"Digital health" describes the engagement with and use of digital technology in ways that promote physical, psychological, and social well-being. A basic requirement of digital health is a positive and respectful approach to technology and online communication. It is a fact that the healthcare system is undergoing major changes due to digital transformation. Therefore, an understanding of global trends and technologies that scale up digital health is a must for leaders both in the health sector and elsewhere. Personalized medicine as well as technological advances in genomics and mobile health are just a part of the ongoing development. With the increasing amount of health data gathered worldwide, big data technologies have also significantly gained in importance for the health sector. As part of this development, new roles are emerging for the population and patients as producers and managers of their own data. Switzerland as a country has a pioneering role in the democratization of personal data and digital health.